Rash Decisions
Dermsquared Case Reports
Follow real-world dermatology cases from presentation through management, test your clinical reasoning, and explore the rationale behind key treatment decisions.
- Clinical reasoning
- Strengthen your diagnostic and treatment approach
- Real-world cases
- Learn through authentic patient presentations
- Interactive experience
- Engage with cases through quizzes and other interactive elements
Case reports
Where dermatology's toughest calls become teachable moments — real cases, real decisions, from the experts shaping how the specialty practices.
Case ReportOct 19, 20261 min
Tapinarof Cream for Pediatric Atopic Dermatitis: Meeting Patient and Caregiver Treatment Needs
Case author Linda Stein Gold, MD, presents a case of a 9-year-old patient with atopic dermatitis whose treatment was complicated by poor tolerability of previous topical therapy and caregiver concerns.
Linda Stein GoldAuthor- Atopic Dermatitis
Case ReportSep 3, 20264 min
Utility of Tapinarof Cream 1% in a Case of Severe and Recalcitrant Atopic Dermatitis In a Pediatric Patient
Case author Naiem T. Issa, MD, PhD, presents a case of a 10-year old white male with a 5-year history of atopic dermatitis, allergic rhinitis and exercise-induced asthma.
- Atopic Dermatitis
Case ReportSep 3, 20262 min
Tapinarof 1% Cream Effectively Clears Plaques of the Boney Prominences
Case author Brad Glick, DO, MPH, FAAD, presents the case of a 57-year-old female with worsening plaque psoriasis of the elbow who experienced limited responses to multiple therapies.
- Psoriasis
Case ReportSep 3, 20263 min
Intravenous and subcutaneous spesolimab use in a medically comorbid patient with erythrodermic generalized pustular psoriasis
Case author Angad Arinder Chadha, MD, presents a case of a 72-year-old African American female admitted for management of a generalized pustular psoriasis (GPP) flare.
- Generalized Pustular Psoriasis (GPP)
Case ReportSep 3, 20265 min
Effective Primary Management of an Exacerbation of Atopic Dermatitis Using a Non-Steroidal Topical Therapy
Case authors Lisa C. Lopez-Sanglay, APRN, FNP-BC and James Q. Del Rosso, DO, FAAD, FAOCD present a case of a 15-year-old male with a flare of atopic dermatitis primarily affecting his hands and feet and a severely pruritic rash.
Case ReportSep 3, 20266 min
Lifelong Atopic Dermatitis with Idiopathic Sudomotor Failure: Response to Lebrikizumab After Dupilumab Failure
Dr Jenny Murase presents a case of severe, dupilumab-refractory atopic dermatitis with idiopathic sudomotor failure successfully managed with lebrikizumab.
- Atopic Dermatitis
Case ReportSep 3, 20263 min
When the Hands Don’t Follow the Rest: Managing Chronic Hand Eczema Despite Systemic AD Control
Dr Jenny Murase presents a case of chronic hand eczema persisting despite well-controlled atopic dermatitis on dupilumab, highlighting the role of delgocitinib cream.
- Chronic Hand Eczema
Case ReportSep 3, 20263 min
Jacked on JAKs: The Therapeutic Impact of Dose Escalation in a Case of Refractory Atopic Dermatitis
Case author Graham Litchman, DO, MS, presents a case of a young adult patient with longstanding atopic dermatitis that remained uncontrolled despite multiple prior therapies, prompting consideration of dose escalation with a JAK inhibitor.
- JAK Inhibitors
Case ReportSep 3, 20263 min
Rapid Clearance of Recalcitrant Psoriasis With an IL-17 Inhibitor
Mark Lebwohl, MD, presents a case of a 48-year-old female with a 10-year history of psoriasis who was successfully treated with an IL-17 inhibitor after inadequate response to both phototherapy and a TNF blocker.
Case ReportSep 3, 20262 min
Subcutaneous Spesolimab Use in a Patient with Chronic Recurrent Generalized Pustular Psoriasis (GPP)
Case author Saakshi Khattri, MD, presents a case of a 61-year-old Asian female with a 30-year history of GPP who experienced a flare after months of remission following intravenous spesolimab, prompting a transition to subcutaneous maintenance therapy.
- Generalized Pustular Psoriasis (GPP)
- Biologics
Case ReportSep 3, 20265 min
A Remarkable Result after a Lifetime of Disappointment in the Treatment of Severe, Recalcitrant Psoriasis
Case author Danna Calder, MMSc, PA-C presents a case of a 34-year-old male with severe, recalcitrant psoriasis achieving remarkable improvement after decades of treatment challenges.
- Psoriasis
Case ReportSep 3, 20263 min
Rapid and sustained clearance of severe psoriasis with dual inhibition of IL-17A and IL-17F
Ron Vender, MD, FRCPC, presents the case of a 31-year-old male with an 8-year history of severe psoriasis who was frustrated with the lack of effective treatment options.
- Psoriasis
Case ReportSep 3, 20262 min
A Case of Nonsegmental Vitiligo on the Face and Hands Treated With Combination Topical JAK Inhibitor and Phototherapy
Case authors Mavra Masood, MD, Jennifer Creasor, BSN, and Iltefat Hamzavi, MD, present a case of a 74-year-old female with persistent generalized vitiligo on the face and body.
- Vitiligo
Case ReportSep 3, 20262 min
Successful Management of Basal Cell Carcinoma in a Challenging Location with a Multimodal Approach
Case author Mark Lebwohl, MD, presents a case of a 86-year-old male with a progressively enlarging erythematous nodular mass with overlying telangiectases.
- Skin Cancer
Case ReportSep 3, 20264 min
Accurately Assessing Prognosis for High-Risk Squamous Cell Carcinoma
Case authors Danny Zakria, MD, MBA, Ryan Rivera-Oyola, MD, and Darrell Rigel, MD, MS, present a case of a 58-year-old male with a history of sun exposure and a skin lesion showing signs of malignancy.
- Skin Cancer
Case ReportSep 3, 20265 min
Successful Treatment of Nonsegmental Periorbital Vitiligo
Case author Stephen W. Lewellis, MD, PhD, FAAD, presents a case of a 38-year-old female with loss of pigmentation on her forehead, cheeks, and eyelids who did not respond to prior treatment with a topical corticosteroid or calcineurin inhibitor.
- Vitiligo
Case ReportSep 3, 20263 min
A Life-Saving Treatment in a 60-year Old Patient With Rapid Eruption of Pustules
Case author Boni Elewski, MD and moderator Danny Zakria, MD, MBA, present a case of a 60-year old female who was airlifted in the middle-of-the-night with a rare dermatologic emergency.