Case author Danna Calder, MMSc, PA-C presents a case of a 34-year-old male with severe, recalcitrant psoriasis achieving remarkable improvement after decades of treatment challenges.

Case author Mark Lebwohl, MD, presents a case of a 86-year-old male with a progressively enlarging erythematous nodular mass with overlying telangiectases.

Case author Brad Glick, DO, MPH, FAAD, presents the case of a 57-year-old female with worsening plaque psoriasis of the elbow who experienced limited responses to multiple therapies.

Ron Vender, MD, FRCPC, presents the case of a 31-year-old male with an 8-year history of severe psoriasis who was frustrated with the lack of effective treatment options.

Case authors Mavra Masood, MD, Jennifer Creasor, BSN, and Iltefat Hamzavi, MD, present a case of a 74-year-old female with persistent generalized vitiligo on the face and body.

Mark Lebwohl, MD, presents a case of a 48-year-old female with a 10-year history of psoriasis who was successfully treated with an IL-17 inhibitor after inadequate response to both phototherapy and a TNF blocker.

Case author Stephen W. Lewellis, MD, PhD, FAAD, presents a case of a 38-year-old female with loss of pigmentation on her forehead, cheeks, and eyelids who did not respond to prior treatment with a topical corticosteroid or calcineurin inhibitor.

Case authors Danny Zakria, MD, MBA, Ryan Rivera-Oyola, MD, and Darrell Rigel, MD, MS, present a case of a 58-year-old male with a history of sun exposure and a skin lesion showing signs of malignancy.

Case author Boni Elewski, MD and moderator Danny Zakria, MD, MBA, present a case of a 60-year old female who was airlifted in the middle-of-the-night with a rare dermatologic emergency.

Case authors Lisa C. Lopez-Sanglay, APRN, FNP-BC and James Q. Del Rosso, DO, FAAD, FAOCD present a case of a 15-year-old male with a flare of atopic dermatitis primarily affecting his hands and feet and a severely pruritic rash.