CSU Beyond the Visible

Chronic spontaneous urticaria (CSU) can appear episodic from the outside, but for many patients, the disease extends far beyond the visible flare. This Experience examines CSU as an unpredictable and deeply disruptive disease state, with expert discussion on the burden patients carry between flares, the limits of repeated antihistamine and corticosteroid cycling, and the evolving role of targeted therapy in longer-term control. As new options change the treatment conversation, the series invites dermatology clinicians to look beyond the exam itself, listen closely to the history, and reconsider CSU as a disease they can recognize, counsel on, and manage with greater intention.