Latest in News & Research
LAUNCH ALERT: FDA Approves Anzupgo (Delgocitinib) Cream for Moderate-to-Severe Chronic Hand Eczema in Adults
The topical pan-JAK inhibitor is the first FDA-approved therapy specifically indicated for chronic hand eczema
40-Gene Expression Profile Predicts Local Recurrence in High-Risk cSCC
Three-year local recurrence-free survival, metastasis-free survival higher for class 1 versus class 2A or 2B patients
Risk for New-Onset Depression, Anxiety Elevated for Patients With Hidradenitis Suppurativa
No consistent differences seen across severity levels using treatment and HS-related surgical procedures as markers of severity
FDA Approves First Cream for Treating Chronic Hand Eczema
Key Takeaways
The U.S. Food and Drug Administration has given its nod to a new treatment for chronic hand eczema
Anzupgo is now the...
Alopecia Areata Associated With Severe Psychosocial Impact
High levels of anxiety, depression, stigma, and impaired QoL reported by many patients; all linked to perceptions of illness
Novel Treatments Recommended for Management of Atopic Dermatitis in Adults
Strong recommendations presented for tapinarof cream, roflumilast cream, lebrikizumab, nemolizumab with concomitant topical therapy
Daily Emollient Application May Reduce Risk for Atopic Dermatitis in Infants
Daily emollient applications starting before age 9 weeks linked to reduction in cumulative incidence of atopic dermatitis at age 24 months
Factors Identified That Affect Dermoscopic Findings in Acral Melanoma
Tumor thickness, lesion diameter, patient sex, and patient age may affect dermoscopic findings
Study Compares Benefits, Harms of Treatments for Chronic Hives
Systematic review and network meta-analysis included 93 trials evaluating 42 interventions
Subclinical Synovitis Risk Higher in Psoriasis Without Musculoskeletal Involvement
Authors say imaging may aid in identifying individuals at risk for progression to psoriatic arthritis
Presurgical Immunotherapy Offers Long-Term Benefit in Melanoma
80 percent of adult patients with stage III/IV resectable melanoma remained event-free at four years from the start of neoadjuvant systemic treatment
Number of Atopic Dermatitis Flares Linked to Lower QoL, More Severe Disease
Flare severity, duration, and number were among most important predictors of AD severity
Neutrophil-to-Lymphocyte Ratio Can ID Risk in Localized Melanoma
NLR level >4.8 associated with increased risk for melanoma-specific death and developing distant metastases
High Dietary Inflammatory Index Tied to Increased Prevalence of Eczema
Significant sex interaction observed, with stronger associations in the female group
Atopic Dermatitis May Be Linked to Increased Risk for CKD
Association between AD and increased risk for chronic kidney disease seen for men and women and in all age groups
Prevalence, Incidence of Eczema Increase With Severity of Alopecia Areata
Those with moderate-to-severe versus mild AA had 78 percent higher risk for being diagnosed with atopic dermatitis
Ichthyosis Scoring System Can Be Applied Across Phototypes
Excellent interrater intraclass correlation coefficients seen for individuals with Fitzpatrick I to III, IV to VI skin types
Distinct Risk Factors Seen for Nevus-Associated, De Novo Melanomas
Significantly higher hazard ratios seen for NAM than de novo melanoma for high nevus density, high genetic propensity for melanoma development
AI Better for Tumor-Infiltrating Lymphocyte Quantification in Melanoma Than Traditional Methods
Machine learning algorithm has superior reproducibility and prognostic associations compared with traditional pathologist-read methods
Review Compares Efficacy, Safety of Treatments for Hidradenitis Suppurativa
Differences between adalimumab and other targeted treatments mainly not significant
Extending Dabrafenib + Trametinib Beneficial in Stage III Melanoma
Extending adjuvant dabrafenib + trametinib beyond one year linked to better relapse-free survival
Increased Levels of Environmental Pollutants Linked to Atopic Dermatitis
Probable associations seen for secondhand smoking exposure and traffic and industrial plant exposure with increased prevalence of atopic dermatitis
Men With Hidradenitis Suppurativa Perceive Better Physician Communication
Female patients perceive that clinicians are significantly worse at demonstrating respect, listening, and explaining concepts
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