Trends of Metformin Use in Patients with Hidradenitis Suppurativa, 2016-2021
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Keywords
Hidradenitis Suppurativa, Metformin, diabetes mellitus, Type 2 diabetes, PCOS, Commercial claims analysis
Abstract
Introduction: Hidradenitis Suppurativa (HS) is a dermatologic condition that is comorbid with diabetes mellitus (DM) and polycystic ovarian syndrome (PCOS). Metformin has been used as a therapy in DM and PCOS but little research has been done to see if it is being used in patients with HS.
Methods: Using MarketScan, information on HS, DM, and PCOS diagnoses were collected from January 1, 2016--December 31, 2021. Metformin prescription information was also collected on these patients.
Results: During the study, the percentage of HS patients with a metformin prescription increased (Z = -9.6, p<0.001). Metformin prescriptions in patients with HS but without DM or PCOS diagnoses also increased (Z= -13.1, p<0.001).
Discussion: Metformin offers promising therapeutic options for the treatment of patients with HS, even if they do not have comorbid conditions.
References
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