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Dermbits

What biologic medication (other than Humira) has worked best in your experience for your moderate to severe HS?

Hidradenitis Suppurativa

So I was very excited when Humira got approval for moderate to severe HS. But there are some patients who do not respond to humira in my practice. What I switch them to is remicade or infleximab, and that seems to work, at least for the humira failure patients. And the advantage of remicade or infleximab is that it is a weight based dosing. There is sort of like a sliding scale of anything from five milligrams per kg to ten milligrams per kg. So that gives me a lot of leeway for increasing the dose. The second way of sort of increasing the dose of remicade is by increasing the frequency. So it's a loading dose of week zero, two, six and every eight weeks thereafter. But depending on lack of response or the kind of response an HS patient has, I can make the dose more frequent. So certainly in my experience, Humira failures, when I switch them to infleximab or remicade, they do show a positive response on.