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Dermbits

MD, MPH

Are there any sensitizing ingredients or irritants in topical roflumilast and does it contain propylene glycol?

Psoriasis

You. So, when we talk about topical reflumolast, we see that this vehicle has the advantage of being water based. It has an emulsifier to deliver the active ingredient while maintaining the epidermal barrier function. When we look for potential sensitizers in the vehicle, luckily, we see an absence of any fragrance, any propylene glycol. There is no isopropyl alcohol or ethanol. So the overall profile, the vehicle of this topical reflumlast looks very favorable, lacking a lot of the common sensitizers.