How does the 40-GEP test work?
Featuring Darrell Rigel, MD, MS | Senior Clinical Advisor |

Clinical Professor of Dermatology 
Director, Melanoma Surveillance Clinic 
Mount Sinai Icahn School of Medicine, New York, NY 
Adjunct Professor, UT Southwestern Medical School 
Consultant Dermatologist, Cooper Clinic, Dallas, TX

| Published August 01, 2023

In the video, Dr. Darrell Rigel explains how the 40-GEP test functions. The test involves the analysis of 40 specific genes to evaluate their expression levels. These genes are used in combination with a proprietary formula to determine a patient's prognosis. Based on the results, patients are categorized into low-risk, medium-risk, or high-risk groups. This classification helps medical professionals make more accurate assessments and tailor the appropriate treatment plan accordingly. 

Key Points 
  • The 40-GEP test utilizes 40 specific genes. 
  • Its primary purpose is to assess prognosis in medical cases. 
  • The test evaluates the degree of gene expression in combination with a proprietary formula. 
  • The evaluation helps categorize patients into different risk groups: low risk, medium risk, or high risk. 
  • The results of the test allow healthcare professionals to tailor treatment plans based on the risk group the patient falls into. 
  • By understanding the patient's risk level, the therapy can be adjusted accordingly to optimize treatment outcomes.

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