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How long should you give any biologic before you decide to switch agents?

Psoriasis

You. Switching medications can be difficult, and determining when and why to switch medications can be based on a number of factors. I certainly want to tease out any external factors that may be resulting in loss of efficacy. Noncompliance is certainly high on that list. Once those have been ferreted out, I will consider changing medications after three months or greater on the initial medication, as long as they're not experiencing an adverse event from the previous medication.