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Dermbits

UCB Bimz October 2023

What is the mechanism of action of bimekizumab and how does it differ from other systemic psoriasis treatments?

Psoriasis

You. We have had some very good IL 17 blockers for treatment of psoriasis. They are fast and they are quite effective. They are effective by blocking IL 17 A, which clearly is the most important cytokine in getting rid of psoriasis. However, bimikish mab now comes along, it turns out to be even faster and more effective, and the reason for that is that it blocks IL 17 A and IL 17 F, and thereby we get an additive effect so that we get a rapider and more effective resolution of psoriasis. Clearing of psoriasis it turns out that while IL 17 A is the most important cytokine to block, IL 17 F also has a psoriasis psoriasis causing effect. And even though IL 17 a clearly has the most psoriasis causing effect, IL 17 F is more prevalent in plaques of psoriasis. So getting rid of both has a bigger advantage and.

What is the mechanism of action of bimekizumab and how does it differ from other systemic psoriasis treatments?

Related CME