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Which patients are eligible for treatment with baricitinib and are there any notable exclusion criteria?

Featuring Michael Cameron, MD |

Assistant Professor
Mount Sinai Ichan School of Medicine
New York, NY

| Published August 01, 2023


In the video, Dr. Michael Cameron discusses the eligibility criteria for treatment with baricitinib and highlights some notable exclusion criteria. According to the label for baricitinib, it is defined as a treatment option for severe alopecia areata. However, there are no specific requirements regarding body surface area involvement. The decision of what constitutes severe alopecia areata and necessitates treatment with baricitinib is left to the provider and the patient to determine. 

In terms of exclusion criteria, it is not recommended to use baricitinib in combination with other systemic immunosuppressants such as methotrexate, prednisone, and azathioprine. This indicates that patients who are already taking these medications should not be considered for baricitinib treatment due to potential adverse effects or interactions. 

In summary, patients eligible for baricitinib treatment are those with severe alopecia areata, as determined by the provider and the patient, and who are not already taking an immunosuppressant. 

Key Points 
  • There are no specific body surface area involvement requirements for eligibility. 
  • The decision on whether a case of alopecia areata is considered severe and requires baricitinib treatment is made jointly by the healthcare provider and the patient. 
  • Baricitinib should not be used in combination with other systemic immunosuppressants such as methotrexate, prednisone, and azathioprine. 
  • Contraindications include concurrent use of baricitinib with certain medications that have immunosuppressive properties.

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