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Dermbits

How does ruxolitinib compare with topical calcineurin inhibitors and topical steroids?

Atopic Dermatitis

This is a great question. In one of the earlier trials, topical ruxalitinib was compared to an active triumphinolone arm in the trials, showing actually and actually outperforming the triumphsinolone arm among many efficacy endpoints. So there we have some relative efficacy comparison against a medium potency topical steroid, which is really, really exciting coming from a non steroidal agent. In terms of comparison to another non steroidal like tacrolimus. We don't have direct head to head data, but my personal opinion is that it would likely outperform our generic tacrolimus as well.