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Dermbits

Do you feel comfortable using topical ruxolitinib in combination with dupilumab?

Atopic Dermatitis

So a lot of people will have patients on dupilumab for their atopic dermatitis, and maybe they're doing pretty good on dupilumab, but they still have some focused areas of atopic dermatitis for which you might want to use a topical medicine. A lot of people wonder, could I use topical ruxolitinib in that situation? In my opinion, I think you can. I think it's actually very effective, well tolerated combination. The one problem is that the official FDA labeling shows a limitation of use, implying that it's not to be combined with any biologic or systemic agent. So sometimes you have a harder time getting it covered by insurance. But I personally love the combination for my patients.