How do you discuss 40-GEP test results with patients?
Clinical Professor of Dermatology
Director, Melanoma Surveillance Clinic
Mount Sinai Icahn School of Medicine, New York, NY
Adjunct Professor, UT Southwestern Medical School
Consultant Dermatologist, Cooper Clinic, Dallas, TX
When I get a result from the 40-GEP test, it's important that I have a frank conversation with patients. What's interesting about these results, it's fairly easy for the patient to understand because there's three levels of risk: low, mid risk, and high risk. Depending on where the patient falls, I will have that discussion with the patient and the idea behind this is using the degree of risk and prognosis, what I can do is talk to the patient about whether additional therapy is needed. Whether we need adjuvant radiation, whether we would use some cemiplimab or a PD1 or more advanced disease. But a low risk patient, I can say with pretty surety, that in fact there's no need to do advanced treatments or other things more than just following the patient close.
Dr. Darrell Rigel discusses how he approaches the discussion of 40-GEP (Genomic Expression Profile) test results with his patients. He emphasizes the importance of having a frank conversation with the patients about their test results. The 40-GEP test results are relatively easy for patients to understand because they are categorized into three levels of risk: low risk, mid-risk, and high risk. Depending on which risk category the patient falls into, Dr. Rigel tailors his discussion accordingly. For patients with low-risk results, Dr. Rigel can confidently inform them that there is no need for advanced treatments or additional therapies beyond close monitoring. However, for patients in the mid-risk or high-risk category, he may discuss the possibility of additional therapies such as adjuvant radiation or the use of specific medications like cemiplimab, PD1 inhibitors, or other more advanced treatments. The primary goal of discussing these test results with patients is to provide them with a clear understanding of their risk level and prognosis. This information allows for informed decision-making regarding the necessity and potential benefits of further treatment options, ensuring the best possible care for each individual patient.
- 40-GEP test results are easy for patients to understand as they are categorized into three levels of risk: low, mid risk, and high risk.
- The degree of risk and prognosis are used to determine whether additional therapy is necessary, and the doctor should tailor their discussion with the patient accordingly.
- Treatment options discussed with mid to high-risk patients may include adjuvant radiation, cemiplimab, PD1 inhibitors, or more advanced treatments.
- For low-risk patients, the need for advanced treatments is deemed unnecessary, and close patient monitoring may suffice.