Episode 16 of Derms and Conditions has our host James Q. Del Rosso, DO speaking with Matthew Zirwas, MD about pruritus. Dr. Zirwas discusses the topical treatment of pruritis and offers a unique combination topical regimen that he often uses for his patients. He also presents some tips and tricks for treating Pruritus Ani. 

Dr. Del Rosso and Dr. Zirwas also discuss a new non-steroidal, topical agent for pruritus. Dr. Zirwas discusses, in detail, the hypothesized mechanism of action for this novel agent and shares his success using it in his clinic. Finally, he briefly mentions some alternative oral agents for the pruritic patient.




Financial Disclosures

JAMES DEL ROSSO, DO FINANCIAL DISCLOSURES:

CONSULTANT/ADVISOR
Abbvie, Aclaris, Almirall, Amgen, Arcutis, Bausch Health (Ortho Dermatology), BioFrontera, BioPharmX, Bristol-Myers-Squibb, Cassiopea, Dermata, Dermavant, Encore, EPI Health, Evommune, Ferndale, Galderma, Incyte, JEM Health, Leo Pharma, La Roche Posay, Lilly (Dermira), MC2, Novan, Pfizer, Regeneron, Sanofi-Genzyme, SolGel, Sonoma (IntraDerm), Sun Pharma, Trevi, UCB, Verrica, Vyne (Foamix; Menlo)

SPEAKER BUREAU
Aclaris, Almirall, Amgen, Arcutis, Bausch Health (Ortho Dermatology), EPI Health, Ferndale, Galderma, Genentech, JEM Health, Leo Pharma, La Roche Posay, Lilly (Dermira), Pfizer, Regeneron, Sanofi-Genzyme, Sun Pharma, UCB, Verrica, Vyne (Foamix; Menlo)

RESEARCH INVESTIGATOR
Aclaris, Almirall, Amgen, Anaptys Bio, Arcutis, Athenex, Bausch Health (Ortho Dermatology), BioPharmX, Biorasi, Botanix, Brickell, Cara Therapeutics, Cassiopea, Dermavant, EPI Health, Ferndale, Galderma, Incyte, Leo Pharma, Lilly (Dermira), Novan, Pfizer, Ralexar, Regeneron, SolGel, Sun Pharma, UCB, Verrica, Vyne (Foamix; Menlo).

MATTHEW ZIRWAS, MD FINANCIAL DISCLOSURES:

Regeneron / Sanofi - Speaker, consultant, investigator
Fit Bit - Consultant
Genench / Novartis - Speaker
L’Oreal - Consultant
Menlo - Consultant
AsepticMD - Part Owner
Leo - Investigator, Consultant
Janssen - Investigator
Incyte - Investigator
Foamix - Investigator
UCB - Investigator
Pfizer - Investigator, consultant
Lilly - Investigator, consultant
Asana - Investigator
Avillion - Investigator
Ortho Derm - Consultant
Abbvie - Investigator
Edessa Biotech - Investigator
Galderma - Investigator
Dermavant - Investigator
Arcutis - Investigator, Consultant
Sol-Gel - Consultant
Bausch Health - Consultant
EPI Health - Consultant, Investigator