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Dermbits

MD, MPH

Did the Phase 3 pivotal studies for roflumilast specifically evaluate itch reduction?

Psoriasis

So the phase three pivotal studies for reflumolast did indeed specifically evaluate itch reduction as a secondary endpoint. In the studies using worst itch NRS success, this was one of the secondary endpoints, and a significantly greater proportion of patients treated with reflumolast cream achieved itch reduction by Wi NRS and compared to vehicle. So yes, we do have itch data.