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Dermbits

What are high risk features of cSCC?

Skin Cancer

What are high risk features for cutaneous squamous cell? Well, it really depends upon who you ask. There's, of course, the four from Brigham and women's. Is it large? Is it down to the fat? Is there perineural invasion, or is it poorly differentiated? But there's other important ones, such as immunosuppression, that they seem to have forgotten. That matters to me. And then also think about other pathologic features as well as clinical features, such as it's growing quite fast, or I care about whether or not there's nerve involvement. It's not always easy to find perineural invasion, but if you tap in the area and they're having some sort of sensation, then you know that guess what? The nerve is likely to be involved as well. So there are lots of high risk features. Years and years of experience really help us identify which features matter for us and for each patient. Thank.