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Dermbits

How do you dose IVIG for dermatomyositis with and without myopathy?

Connective Tissue Diseases

The dose of IVIG for DM is sort of same for whether it's skin or muscle, and it is 2 grams/kg total dose, which can be equally divided on anything from two to five days. In my practice I do divide that over a three day period, and I repeat it every four weeks for the first six months. And depending on clinical response, after six months, if a patient has sort of either gone into remission or they've improved complete significantly, you can decrease the dose to 1 gram per kg body weight again on three divided three days. So IVIg is a good option for both DM with or without muscle involvement, and certainly for skin DM it's very efficacious.