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Dermbits

Do you compound any currently available JAK inhibitors into creams for topical use by your patients?

JAK Inhibitors

You? I do. I recommend typically topical topacidinib, which we have mixed up in a 2% topical ointment, and we use it for our alopecia patients. I haven't found it to be greatly successful on the scalp, but in my patients with eyebrow involvement, we sometimes do find that it can be very helpful. I've had a few patients who've used it for vitiligo, and again, it's usually the topical topacidinib. I have compounded ruxalidinib as well, but that's a little less commonly used and a little bit more expensive, in my experience. So I've used topacidinib, the topical topacidinib, and that's worked out pretty well for patients. There are some people who feel that the mixture where I've been compounding it is a little tingly when they put it on, but it kind of goes away very quickly, so people tolerate it quite well.